Description

Clevudine is a synthetic nucleoside analogue with potent antiviral activity. It is a critical active pharmaceutical ingredient (API) primarily valued for its targeted mechanism of action against viral replication. This compound is essential for pharmaceutical manufacturers and research institutions developing antiviral therapies. Its specific activity profile makes it a key component in advanced therapeutic formulations.

Application

• Antiviral Drug Synthesis: Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of antiviral medications.
• Hepatitis B Virus (HBV) Research: A vital reference standard and investigational compound in virology and antiviral drug discovery programs targeting HBV.
• Pharmaceutical Intermediates: Serves as a key building block in the multi-step synthesis of more complex nucleoside-based therapeutics.
• Biochemical Research: Used in enzymatic studies and as a probe to understand nucleoside metabolism and viral polymerase inhibition mechanisms.
• Formulation Development: Employed in the R&D of solid dosage forms (tablets, capsules) and other drug delivery systems.
• Reference Standard: Utilized as a high-purity certified reference material (CRM) for quality control and analytical method development in QC laboratories.

Basic Information

Product Name	Clevudine
CAS No.	172494-45-0
Molecular Formula	C10H13FN2O5
Molecular Weight	260.22 g/mol
Synonyms	1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyluracil; L-FMAU; 2'-Fluoro-5-methyl-β-L-arabinofuranosyluracil; FMAU; Clevudine; L-Fd4C; Reverset (developmental code name); L-2'-Fd4C
EINECS	Contact for details

Quality Control

Our Clevudine is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each batch. We can support compliance with relevant pharmacopeial guidelines (e.g., USP, EP) for API specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.