Description

Brasofensine CAS NO 171655-91-7 is a selective and potent dopamine reuptake inhibitor (DRI) belonging to the tetralin class of compounds. This compound is of significant interest for its potential to modulate dopaminergic neurotransmission, a key pathway in the central nervous system. It is primarily utilized by pharmaceutical researchers and developers in the fields of neuroscience and neuropharmacology for investigative and developmental purposes.

Application

• Neuroscience Research: A key reference standard and active compound for studying dopamine transporter (DAT) function and dopamine reuptake inhibition mechanisms.
• Pharmacological Studies: Used in in vitro and in vivo models to investigate the effects of selective dopamine reuptake inhibition on behavior and neurochemistry.
• Drug Discovery & Development: Serves as a crucial chemical tool or lead compound in the research and development of novel therapeutics for central nervous system (CNS) disorders.
• Biochemical Assays: Employed as a ligand in receptor binding assays and other biochemical tests to screen for activity at the dopamine transporter.
• Reference Material: Provides a high-purity benchmark for analytical method development, validation, and quality control in research and pre-clinical settings.

Basic Information

Item	Details
Product Name	Brasofensine
CAS No.	171655-91-7
Molecular Formula	C17H21NO2
Molecular Weight	271.36 g/mol
Synonyms	(+)-NS 2330; (6R)-6-(4-Methylphenyl)-5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline; Brasofensine hydrochloride; BMS-204756; PNU-99,194; (6R)-6-(p-Tolyl)-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline
EINECS	Contact for details

Quality Control

Our Brasofensine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.