Description

(R,R)-3,4-Diamino-2,2,5,5-Tetramethylhexane is a high-purity, chiral diamine building block of significant interest in advanced organic synthesis. Its value lies in its rigid, sterically hindered structure, which makes it an excellent ligand for asymmetric catalysis and a key precursor for the synthesis of complex chiral molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for developing novel active ingredients and functional materials.

Application

• Asymmetric Catalyst Ligand: Serves as a chiral backbone for constructing transition metal complexes used in enantioselective hydrogenation, hydroformylation, and other catalytic transformations.
• Pharmaceutical Intermediate: A critical building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for optimal activity.
• Chiral Resin & Polymer Precursor: Incorporated into the synthesis of chiral stationary phases for chromatography and into specialty polymers with unique optical or mechanical properties.
• Chelating Agent for Metal Scavenging: Its diamino structure is effective in binding and removing trace metal impurities from reaction mixtures or final products.
• Academic & Process R&D: A valuable reagent for methodological development in organic chemistry and for scaling up novel synthetic routes in process chemistry.

Basic Information

Item	Details
Product Name	(R,R)-3,4-Diamino-2,2,5,5-Tetramethylhexane
CAS No.	171357-23-6
Molecular Formula	C10H24N2
Molecular Weight	172.31 g/mol
Synonyms	(R,R)-2,2,5,5-Tetramethyl-3,4-diaminohexane; (3R,4R)-3,4-Diamino-2,2,5,5-tetramethylhexane; (R,R)-TMHD; (R,R)-TMDH; (R,R)-Diaminotetramethylhexane; (R,R)-DATH; (1R,2R)-1,2-Bis(1,1-dimethylethyl)-1,2-ethanediamine (alternative IUPAC); (R,R)-N,N'-Di-tert-butyl-1,2-ethanediamine
EINECS	Contact for details

Quality Control

Our production of (R,R)-3,4-Diamino-2,2,5,5-Tetramethylhexane adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.