Description

Zanamivir Hydrate CAS NO 171094-50-1 is a potent and selective neuraminidase inhibitor, representing a critical class of antiviral agents. Its primary value lies in its ability to effectively treat and prevent infections caused by influenza A and B viruses by inhibiting viral replication and release from host cells. This active pharmaceutical ingredient (API) is essential for manufacturers in the global pharmaceutical industry developing antiviral medications, particularly for high-risk patient populations.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of antiviral drugs for the treatment of influenza.
• Key component in inhalation powders (e.g., Rotadisk®), the primary delivery system for rapid pulmonary administration.
• Manufacturing of prophylactic treatments for seasonal and pandemic influenza outbreaks.
• Use in clinical research and development of next-generation neuraminidase inhibitors.
• Reference standard in analytical laboratories for quality control and method validation of antiviral products.
• Potential applications in veterinary medicine for managing influenza in animal populations.

Basic Information

Product Name	Zanamivir Hydrate
CAS No.	171094-50-1
Molecular Formula	C12H20N4O7 · xH2O
Molecular Weight	332.31 g/mol (anhydrous basis)
Synonyms	Zanamivir; GG167; 5-Acetamido-4-guanidino-2,3,4,5-tetradeoxy-7-O-methyl-D-glycero-α-D-galacto-non-2-enopyranos-1-onic acid hydrate; 4-Guanidino-2,4-dideoxy-7-O-methyl-N-acetylneuraminic acid hydrate; Relenza (Brand Name); GR 121167X; ZAN-01
EINECS	Contact for details

Quality Control

Our Zanamivir Hydrate is manufactured under strict quality management systems, targeting compliance with ICH guidelines and current Good Manufacturing Practice (GMP) standards for active pharmaceutical ingredients. Each batch undergoes comprehensive analytical testing, including identity, purity, and impurity profile determination via advanced techniques like HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and regulatory support for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 10.0% w/w
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.