Description

Zanamivir Hydrate is a potent and selective neuraminidase inhibitor, a critical class of antiviral agents. Its primary value lies in its ability to treat and prevent infections caused by influenza A and B viruses by blocking the release of viral particles from infected cells. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing and producing antiviral medications, particularly for high-risk populations in the global healthcare market.

Application

• Antiviral Drug Manufacturing: Primary active ingredient in the formulation of prescription antiviral medications for influenza.
• Prophylactic Treatment Development: Used in R&D and production of preventative treatments for seasonal influenza outbreaks.
• Hospital & Clinical Formulations: Sourced for compounding or manufacturing specialized dosage forms for hospital use.
• Generic Pharmaceutical Production: Key raw material for manufacturers producing generic versions of neuraminidase inhibitor drugs.
• Biomedical Research: Serves as a reference standard and tool compound in virology and antiviral mechanism studies.
• Pandemic Preparedness Stockpiling: Supplied for government and institutional stockpiles as part of strategic reserves against potential influenza pandemics.

Basic Information

Product Name	Zanamivir Hydrate
CAS No.	171094-49-8
Molecular Formula	C12H20N4O7 • xH2O
Molecular Weight	332.31 g/mol (anhydrous basis)
Synonyms	Zanamivir; GG167; 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid; 5-Acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid; Relenza (Brand Name API); Neuraminidase Inhibitor GG167; GR 121167X; ZAN
EINECS	Contact for details

Quality Control

Our Zanamivir Hydrate is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Quality is verified through comprehensive analytical testing, including HPLC for purity, chiral purity determination, and stringent control of related substances and residual solvents. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, supporting compliance with cGMP and relevant pharmacopeial guidelines (USP/EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC, anhydrous basis)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	As per hydrate specification
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	< 5.0 EU/mg
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.