Description

(R)-(-)-5,5-Dimethyl-4-Phenyl-2-Oxazolidinone is a high-value chiral auxiliary and building block in asymmetric synthesis. This compound matters because it provides a rigid, non-racemic framework essential for inducing stereoselectivity in critical bond-forming reactions, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and complex organic molecules.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to control stereochemistry in aldol, alkylation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: Key building block for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs), especially in neurology and cardiology.
• Agrochemical Research: Employed in the development of chiral herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in metal-catalyzed transformations.
• Academic & Process Chemistry: A standard reagent in methodological research for new asymmetric methodologies and scale-up process development.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high optical purity for electronics or perfumery.

Basic Information

Product Name	(R)-(-)-5,5-Dimethyl-4-Phenyl-2-Oxazolidinone
CAS No.	170918-42-0
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(R)-5,5-Dimethyl-4-phenyl-2-oxazolidinone; (4R)-5,5-Dimethyl-4-phenyl-1,3-oxazolidin-2-one; (R)-4-Phenyl-5,5-dimethyl-2-oxazolidinone; (R)-(-)-4-Phenyl-5,5-dimethyl-2-oxazolidinone; (R)-Dimethylphenyloxazolidinone; Evans Chiral Auxiliary Derivative; (R)-DMPO
EINECS	Contact for details

Quality Control

Our (R)-(-)-5,5-Dimethyl-4-Phenyl-2-Oxazolidinone is manufactured under strict quality systems to ensure batch-to-batch consistency and high optical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination. Certificates of Analysis (COA) detailing purity, identity, and specific rotation are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]20/D	-80° to -90° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.