Description

2-Bromo-4-Chloro-3-Fluorobenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile and valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce specific halogenated aromatic motifs into target compounds, influencing their bioactivity and physicochemical characteristics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores to modulate receptor binding, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo, chloro, and fluoro substituents can enhance biological activity and environmental persistence profiles.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing chemical probes, tags, and linkers used in studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, halogenated compounds for clients.

Basic Information

Product Name	2-Bromo-4-Chloro-3-Fluorobenzoic Acid
CAS No.	170108-06-2
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	3-Fluoro-2-bromo-4-chlorobenzoic Acid; 4-Chloro-3-fluoro-2-bromobenzoic Acid; Benzoic acid, 2-bromo-4-chloro-3-fluoro-; 2-Bromo-4-chloro-3-fluorobenzoic acid; BCFBA; 170108-06-2; 2-Br-4-Cl-3-F-BA
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Chloro-3-Fluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and titration methods. Our quality commitment ensures material consistency and reliability for your critical synthesis workflows, supporting compliance with cGMP and ISO 9001 standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.