Description

Robalzotan CAS NO 169758-66-1 is a selective and potent serotonin 5-HT1A receptor antagonist. This compound is of significant interest in neuroscience research and pharmaceutical development for its potential to modulate serotonergic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of central nervous system disorders, depression, and anxiety.

Application

• Neuroscience Research: A critical tool for investigating the role of 5-HT1A receptors in brain function and behavior.
• Pharmacological Studies: Used in in vitro and in vivo assays to characterize receptor binding affinity and functional activity.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel psychotherapeutic agents targeting depression and anxiety.
• Biochemical Assays: Employed in high-throughput screening (HTS) and mechanism-of-action studies within pharmaceutical R&D.
• Academic Research: Supports university and institutional research programs focused on neuropharmacology and neuropsychiatric disease models.

Basic Information

Product Name	Robalzotan
CAS No.	169758-66-1
Molecular Formula	C20H24N2O3
Molecular Weight	340.42 g/mol
Synonyms	NAD-299; (R)-3-(Dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide; (R)-3-(Dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide; Robalzotan hydrochloride; (R)-Robalzotan; 5-HT1A receptor antagonist NAD-299
EINECS	Contact for details

Quality Control

Our Robalzotan is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.