Description

(-)-Tianeptine Monosodium Salt is the active pharmaceutical ingredient (API) form of the atypical tricyclic antidepressant agent. This high-purity monosodium salt form offers enhanced stability and solubility for precise formulation work. It is essential for pharmaceutical R&D, reference standard preparation, and the development of novel therapeutic agents targeting neurological pathways. CAS No. 169293-32-7.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the research, development, and production of antidepressant medications.
• Reference Standard & Analytical Testing: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Neuroscience & Pharmacology Research: A critical tool for in-vitro and in-vivo studies investigating mechanisms of action related to mood disorders, neuroplasticity, and glutamatergic systems.
• Preclinical Formulation Development: Used in the development of various dosage forms for pharmacokinetic and efficacy studies.
• Biochemical Assay Development: Employed as a key reagent in developing high-throughput screening assays for drug discovery.

Basic Information

Product Name	(-)-Tianeptine Monosodium Salt
CAS No.	169293-32-7
Molecular Formula	C21H24ClN2NaO4S
Molecular Weight	458.94 g/mol
Synonyms	Tianeptine Sodium Salt; Tianeptine Na; Stablon (brand name); Coaxil (brand name); 7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid monosodium salt; (RS)-Tianeptine Sodium; S 1574.
EINECS	Contact for details

Quality Control

Our (-)-Tianeptine Monosodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for assay and impurity profiling, residual solvent analysis, and identity confirmation (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤5.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.