Description

3'-Trifluoromethylbiphenyl-3-Carboxylic Acid is a high-purity, versatile biphenyl carboxylic acid derivative distinguished by its trifluoromethyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the biphenyl core contributes to structural rigidity and electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and imaging applications.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3'-Trifluoromethylbiphenyl-3-Carboxylic Acid
CAS No.	168619-05-4
Molecular Formula	C14H9F3O2
Molecular Weight	266.22 g/mol
Synonyms	[3-(3-Trifluoromethylphenyl)]benzoic Acid; 3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic Acid; 3-Carboxy-3'-trifluoromethylbiphenyl; Biphenyl-3-carboxylic acid, 3'-trifluoromethyl-; 3'-Trifluoromethylbiphenyl-3-carboxylic acid; 3-(3'-Trifluoromethylphenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethylbiphenyl-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.