Description

(S)-Tetrahydro-3-Furancarboxylic Acid is a high-value chiral building block and key intermediate in organic synthesis. Its defined stereochemistry and functionalized furan ring structure make it essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by pharmaceutical, agrochemical, and advanced materials research sectors for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Polymer Science: Acts as a monomer or co-monomer for creating novel biodegradable or functional polymers with specific properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-Tetrahydro-3-Furancarboxylic Acid
CAS No.	168395-26-4
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(S)-3-Tetrahydrofurancarboxylic Acid; (S)-Tetrahydrofuran-3-carboxylic Acid; (3S)-Oxolane-3-carboxylic Acid; (S)-THF-3-Carboxylic Acid; L-Tetrahydro-3-furanoic Acid; (S)-(-)-Tetrahydro-3-furoic Acid; (S)-3-Carboxytetrahydrofuran
EINECS	Contact for details

Quality Control

Our (S)-Tetrahydro-3-Furancarboxylic Acid is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.