Description

3,4-Difluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures for enhanced activity and environmental profile.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as those used in OLEDs and semiconductors, where fluorination tunes electronic properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and as a building block for functionalized porous materials like MOFs and COFs.
• Chemical Biology & Diagnostics: Utilized in the synthesis of molecular probes, biomarkers, and other tools for life science research and diagnostic applications.

Basic Information

Product Name	3,4-Difluorophenylboronic Acid
CAS No.	168267-41-2
Molecular Formula	C6H5BF2O2
Molecular Weight	157.92 g/mol
Synonyms	(3,4-Difluorophenyl)boronic Acid; B-(3,4-Difluorophenyl)boronic Acid; 3,4-Difluorobenzeneboronic Acid; 3,4-Difluorophenyl-Boric Acid; 3,4-DFPBA; 168267-41-2; Boronic acid, B-(3,4-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3,4-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.