Description

Ethyl 4-Fluoro-2-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role in introducing the 4-fluoro-2-(trifluoromethyl)benzoate moiety, a key structural motif that can impart desirable properties like metabolic stability and lipophilicity to target molecules. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique chemical resistance, thermal stability, or optical properties.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the creation of novel compound libraries for screening.
• Fluorine Chemistry Reagent: Acts as a versatile reagent for introducing fluorinated aromatic systems into more complex molecular architectures.

Basic Information

Product Name	Ethyl 4-Fluoro-2-(Trifluoromethyl)Benzoate
CAS No.	167758-89-6
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 4-Fluoro-2-(trifluoromethyl)benzoate; Benzoic acid, 4-fluoro-2-(trifluoromethyl)-, ethyl ester; 4-Fluoro-2-(trifluoromethyl)benzoic Acid Ethyl Ester; Ethyl 4-Fluoro-α,α,α-trifluoro-o-toluate; 2-(Trifluoromethyl)-4-fluorobenzoic Acid Ethyl Ester; Ethyl 4-Fluoro-2-trifluoromethylbenzoate; 167758-89-6; EINECS Contact for details

Quality Control

Every batch of Ethyl 4-Fluoro-2-(Trifluoromethyl)Benzoate is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting customer and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for each lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.