Description

3-(2,6-Difluorophenyl)Propionic Acid is a high-value fluorinated aromatic building block with the CAS registry number 167683-63-8. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating bioactivity and metabolic stability. It is primarily sought after by research chemists and process development scientists working on novel active ingredients, including non-steroidal anti-inflammatory drugs (NSAIDs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, especially potential COX-2 inhibitors and other anti-inflammatory agents.
• Agrochemical Synthesis: Used as a key building block for developing advanced herbicides and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a starting material for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy.
• Organic Synthesis & Research: A versatile reagent for introducing the 2,6-difluorophenylpropionyl moiety into more complex organic frameworks in academic and industrial R&D.
• Material Science: Employed in the creation of specialty polymers and advanced materials where fluorine incorporation improves chemical resistance and thermal stability.

Basic Information

Product Name	3-(2,6-Difluorophenyl)Propionic Acid
CAS No.	167683-63-8
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,6-Difluorohydrocinnamic Acid; 3-(2,6-Difluorophenyl)propanoic Acid; β-(2,6-Difluorophenyl)propionic Acid; (2,6-Difluorophenyl)propionic Acid; 2,6-Difluoro-β-phenylpropionic Acid; 3-(2,6-Difluorophenyl)propionsäure (German); NSC 405124; 167683-63-8
EINECS	Contact for details

Quality Control

Our 3-(2,6-Difluorophenyl)Propionic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.