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(2R)-(-)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine CAS NO 166764-19-8


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CAS No.:166764-19-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R)-(-)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine is a high-purity chiral diamine compound of significant interest in advanced organic synthesis. Its value lies in its role as a sophisticated building block and chiral auxiliary for the preparation of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development chemists and process scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-stereochemical fidelity intermediates.

Application

  • As a key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
  • Utilized as a ligand precursor or organocatalyst in asymmetric synthesis reactions.
  • Employed in research for developing novel therapeutic agents targeting neurological and cardiovascular diseases.
  • Serves as a building block for advanced materials and specialty polymers with tailored properties.
  • Used in the development of analytical standards and reference materials for quality control laboratories.

Basic Information

Product Name (2R)-(-)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine
CAS No. 166764-19-8
Molecular Formula C20H28N2O2
Molecular Weight 328.45 g/mol
Synonyms (2R)-1,1-Bis(4-methoxyphenyl)-3-methylbutane-1,2-diamine; (R)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine; (-)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine; (2R)-1,1-Di(4-methoxyphenyl)-3-methyl-1,2-butanediamine; (R)-DMBDA; Chiral DMBDA; (R)-(-)-DMBDA
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Quality Control

Our (2R)-(-)-1,1-Bis(4-Methoxyphenyl)-3-Methyl-1,2-Butanediamine is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity, and identity. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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