Description

Bicyclo[2.2.2]Octan-2-Amine, (S)- (9Ci) is a high-purity, chiral amine building block characterized by its rigid, three-dimensional bicyclic framework. This compound is of significant value in advanced organic synthesis, particularly for introducing steric and stereochemical complexity into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, chiral ligand development, and the creation of novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting the central nervous system.
• Chiral Ligand & Catalyst Precursor: Serves as a foundational structure for synthesizing novel ligands used in asymmetric catalysis, such as hydrogenation or C-C bond formation.
• Agrochemical Research: Used in the discovery and synthesis of new chiral pesticides and herbicides where the specific stereochemistry is critical for biological activity.
• Material Science Building Block: Employed in the synthesis of specialty polymers, dendrimers, or metal-organic frameworks (MOFs) that require rigid, three-dimensional amine components.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry and for probing structure-activity relationships (SAR) in medicinal chemistry programs.

Basic Information

Product Name	Bicyclo[2.2.2]Octan-2-Amine, (S)- (9Ci)
CAS No.	163580-79-8
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	(S)-2-Aminobicyclo[2.2.2]octane; (S)-Bicyclo[2.2.2]octan-2-amine; (2S)-Bicyclo[2.2.2]octan-2-amine; (S)-2-Bicyclo[2.2.2]octylamine; (S)-Aminobicyclo[2.2.2]octane; (S)-2-Norbornaneamine (related); (S)-2-ABCO; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octan-2-Amine, (S)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.