Description

Vilazodone is a modern, potent serotonin modulator and stimulator (SMS) belonging to the azapirone class of compounds. This active pharmaceutical ingredient (API) is critical for the formulation of antidepressant medications, offering a dual mechanism of action that combines serotonin reuptake inhibition with 5-HT1A receptor partial agonism. It is primarily required by pharmaceutical manufacturers and research organizations engaged in the development and production of treatments for major depressive disorder (MDD).

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antidepressant tablets for the treatment of Major Depressive Disorder (MDD).
• Clinical Research: Serves as a reference standard and investigational compound in pharmacological and neuropsychiatric studies.
• Generic Drug Development: A key component for companies developing bioequivalent generic versions of branded antidepressant medications.
• Formulation R&D: Used in the research and development of novel drug delivery systems, such as controlled-release formulations.
• Analytical Standard: Employed as a high-purity standard for quality control testing, method validation, and regulatory submissions.

Basic Information

Product Name	Vilazodone
CAS No.	163521-12-8
Molecular Formula	C26H27N5O2
Molecular Weight	441.52 g/mol
Synonyms	Vilazodone Hydrochloride (common salt form); SB-659746A; 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide; EMD-68843; Viibryd (Brand Name); Vilazodone HCl; 2-Benzofurancarboxamide, 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-
EINECS	Contact for details

Quality Control

Our Vilazodone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed-upon standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the material must be protected from moisture. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.