Description

Clevudine CAS NO 163252-36-6 is a potent synthetic nucleoside analogue with significant antiviral activity. This compound is of critical importance in pharmaceutical research and development, particularly for targeting viral replication mechanisms. It is primarily required by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in antiviral drug discovery and development.

Application

• Antiviral Drug Development: A key active pharmaceutical ingredient (API) and intermediate in the research and synthesis of novel antiviral therapeutics.
• Hepatitis B Virus (HBV) Research: Used extensively in preclinical and clinical studies targeting the treatment of chronic hepatitis B infection.
• Biochemical Research: Serves as a crucial tool compound for studying viral polymerase inhibition and nucleoside metabolism pathways.
• Pharmaceutical Intermediates: Employed in the multi-step synthesis of more complex antiviral agents and prodrugs.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Clevudine
CAS No.	163252-36-6
Molecular Formula	C10H13FN2O5
Molecular Weight	260.22 g/mol
Synonyms	L-FMAU; 2'-Fluoro-5-methyl-β-L-arabinofuranosyluracil; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyluracil; FMAU; Clevudine; L-FMAU; Reverset (developmental code name); L-2'-FMAU
EINECS	Contact for details

Quality Control

Our Clevudine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities to meet research and pharmaceutical-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.