Description

(S,S)-[2-(4'-I-Propyloxazolin-2'-Yl)Ferrocenyldiphenylphosphine is a highly specialized chiral ferrocenyl phosphine ligand, a cornerstone in advanced asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in catalytic reactions, which is critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalysis: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of active pharmaceutical ingredients (APIs) requiring high optical purity.
• Asymmetric C-C Bond Formation: Facilitates critical reactions like cross-couplings and allylic substitutions with excellent stereoselectivity.
• Agrochemical Product Development: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organometallic chemistry and catalysis research.
• Fine Chemical Production: Enables the manufacture of high-value chiral flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	(S,S)-[2-(4'-I-Propyloxazolin-2'-Yl)Ferrocenyldiphenylphosphine
CAS No.	163169-29-7
Molecular Formula	C30H30FeNOP
Molecular Weight	507.39 g/mol
Synonyms	(S,S)-[2-(4'-Isopropyloxazolin-2'-yl)ferrocenyl]diphenylphosphine; (S,S)-2-[2-(Diphenylphosphino)ferrocenyl]-4-isopropyl-4,5-dihydrooxazole; Josiphos SL-J009-1; (S,S)-JOSIPHOS Type Ligand; (S,S)-Fe-Phox Ligand; (S,S)-Ferrocenyloxazolinylphosphine; Chiral Ferrocenyl Phosphine Ligand
EINECS	Contact for details

Quality Control

Every batch of (S,S)-[2-(4'-I-Propyloxazolin-2'-Yl)Ferrocenyldiphenylphosphine is produced and tested under strict quality management protocols to ensure consistency and reliability for catalytic applications. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.