Description

3-Oxazolidinecarboxylic Acid, 2-(1,1-Dimethylethyl)-4-Methylene-5-Oxo-, Phenylmethyl Ester, (2S)- is a high-value, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block in the creation of new, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Synthesis: Serves as a versatile starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric excess.
• Peptidomimetics Development: Employed in the design and synthesis of peptidomimetic compounds, which mimic peptides but offer greater metabolic stability.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value specialty chemicals for research and commercial applications.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs at universities and research institutes.

Basic Information

Product Name	3-Oxazolidinecarboxylic Acid, 2-(1,1-Dimethylethyl)-4-Methylene-5-Oxo-, Phenylmethyl Ester, (2S)-
CAS No.	163084-89-7
Molecular Formula	C16H19NO4
Molecular Weight	289.33 g/mol
Synonyms	(2S)-2-(tert-Butyl)-4-methylene-5-oxo-3-oxazolidinecarboxylic acid phenylmethyl ester; Benzyl (2S)-2-(tert-butyl)-4-methylene-5-oxo-1,3-oxazolidine-3-carboxylate; (S)-Benzyl 2-(tert-butyl)-4-methylene-5-oxooxazolidine-3-carboxylate; (S)-N-Cbz-2-(tert-butyl)-4-methylene-5-oxooxazolidine-3-carboxylic acid; Chiral oxazolidinone derivative; (2S)-2-tert-Butyl-4-methylidene-5-oxo-1,3-oxazolidine-3-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets the high-purity requirements for research and process development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and impurity profiles are available upon request. Our quality system supports development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maximize stability. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.