Description

Nebostinel CAS NO 163000-63-3 is a high-purity synthetic compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a key intermediate or active pharmaceutical ingredient (API) for novel therapeutic agents targeting the central nervous system. This product is essential for research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of next-generation neuropharmaceuticals.

Application

• Critical intermediate in the synthesis of novel neuroactive pharmaceutical compounds.
• Research and development of potential therapeutics for neurological disorders.
• Pre-clinical and clinical trial material for drug discovery programs.
• Production of high-value Active Pharmaceutical Ingredients (APIs) in cGMP environments.
• Reference standard for analytical method development and quality control laboratories.
• Building block for specialized fine chemical and custom synthesis projects.

Basic Information

Product Name	Nebostinel
CAS No.	163000-63-3
Molecular Formula	C15H14N2O3S
Molecular Weight	302.35 g/mol
Synonyms	Nebostinel; 1,2-Benzisothiazol-3-acetic acid, 1,1-dioxide, 2-[(4-methoxyphenyl)methyl]hydrazide; GLYX-13; (R)-GLYX-13; Rapastinel; NMDA receptor modulator; 4-Methoxyphenylmethyl 1,2-dihydro-2-oxo-3H-1,2-benzisothiazol-3-ylideneacetate 1,1-dioxide
EINECS	Contact for details

Quality Control

Our Nebostinel is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and NMR. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.