Description

Ritonavir CAS NO 162990-01-4 is a potent antiretroviral protease inhibitor. It is a critical active pharmaceutical ingredient (API) used in the formulation of combination therapies for the treatment of HIV-1 and HIV-2 infections. This compound is essential for pharmaceutical manufacturers and research institutions developing antiviral medications, particularly in fixed-dose combination products to enhance bioavailability and efficacy.

Application

• Pharmaceutical API: Primary use as the active ingredient in antiretroviral drug formulations for HIV treatment.
• Combination Therapy: Key component in highly active antiretroviral therapy (HAART) regimens, often co-formulated with other protease inhibitors like Lopinavir.
• Bioavailability Enhancer: Used as a pharmacokinetic booster (CYP3A4 inhibitor) to increase the plasma concentration and half-life of other co-administered drugs.
• Research & Development: Vital reference standard and intermediate in virology research and the development of new antiviral agents.
• Generic Drug Manufacturing: Sourcing for the production of cost-effective, quality-assured generic versions of branded antiretroviral medications.

Basic Information

Product Name	Ritonavir
CAS No.	162990-01-4
Molecular Formula	C37H48N6O5S2
Molecular Weight	720.95 g/mol
Synonyms	Norvir; ABT-538; RTV; 5-Thiazolylmethyl [(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenyl-hexan-2-yl]carbamate; L-735,524; Thiazolyl Carbamate
EINECS	Contact for details

Quality Control

Our Ritonavir is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines and can support regulatory filings with relevant documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.