Description

3-(Difluoromethoxy)-4-Methoxybenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique difluoromethoxy and methoxy substituents, which are critical for modulating the physicochemical properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluoromethoxy group can improve activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Used in methodological studies and as a building block for creating complex molecular libraries in discovery chemistry.

Basic Information

Product Name	3-(Difluoromethoxy)-4-Methoxybenzoic Acid
CAS No.	162401-65-2
Molecular Formula	C9H8F2O4
Molecular Weight	218.16 g/mol
Synonyms	4-Methoxy-3-(difluoromethoxy)benzoic acid; Benzoic acid, 3-(difluoromethoxy)-4-methoxy-; 3-(Difluoromethoxy)-p-anisic acid; 3-(Difluoromethoxy)-4-methoxy-benzoic acid; 4-Methoxy-3-difluoromethoxybenzoic acid; DFMBA; 162401-65-2
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)-4-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.