Description

(2R,6R)-2,6-Dimethylpiperazine Dihydrochloride is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its defined stereochemistry is essential for creating active pharmaceutical ingredients (APIs) with specific and potent biological activity. This compound is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing advanced therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly for central nervous system (CNS) agents and antibiotics.
• Ligand for Asymmetric Catalysis: Used in the preparation of chiral catalysts and ligands for enantioselective synthesis.
• API Development: Serves as a core structural component in the research and development of new active pharmaceutical ingredients.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and novel synthetic pathways.
• Fine Chemical Synthesis: A valuable intermediate for producing specialty chemicals with high stereochemical purity requirements.

Basic Information

Product Name	(2R,6R)-2,6-Dimethylpiperazine Dihydrochloride
CAS No.	162240-93-9
Molecular Formula	C6H14N2·2HCl
Molecular Weight	195.11 g/mol
Synonyms	(2R,6R)-2,6-Dimethylpiperazine Dihydrochloride; (R,R)-2,6-Dimethylpiperazine Dihydrochloride; (2R,6R)-2,6-Dimethylpiperazine Hydrochloride; (R,R)-2,6-Dimethylpiperazine Hydrochloride; (2R,6R)-DMPP·2HCl; (R,R)-DMPP·2HCl; 2,6-Dimethylpiperazine Dihydrochloride (R,R)-isomer; (2R,6R)-2,6-Dimethylpiperazine dihydrochloride salt
EINECS	Contact for details

Quality Control

Our (2R,6R)-2,6-Dimethylpiperazine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high stereochemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.