Description

3-Bromo-2-Fluorobenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating fluorinated analogs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine and bromine substituents modulate biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transport or host materials in OLED device fabrication.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) to create biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	3-Bromo-2-Fluorobenzoic Acid
CAS No.	161957-56-8
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	2-Fluoro-3-bromobenzoic Acid; 3-Bromo-2-fluorobenzoic Acid; Benzoic acid, 3-bromo-2-fluoro-; 3-Bromo-2-fluoro-benzoic acid; 161957-56-8; 2-Fluoro-3-bromobenzoic acid; 3-Brom-2-fluorbenzoesäure (German); Acide 3-bromo-2-fluorobenzoïque (French)
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥99.0% (High Purity Grade)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.