Description

Amprenavir is a potent and selective protease inhibitor used in antiretroviral therapy. This active pharmaceutical ingredient (API) is critical for the formulation of medications that combat Human Immunodeficiency Virus (HIV) infection. It is essential for pharmaceutical manufacturers and research institutions developing treatments for HIV/AIDS, particularly in combination therapies aimed at managing drug resistance.

Application

• Antiretroviral Drug Formulation: Primary active ingredient in HIV-1 protease inhibitor medications.
• Combination Therapy (HAART): Used in Highly Active Antiretroviral Therapy regimens to improve efficacy and reduce viral load.
• Pharmaceutical Research: Reference standard and building block for the development of new protease inhibitors and related antiviral compounds.
• Clinical Trial Materials: Sourced for the production of drugs used in clinical studies for HIV treatment.
• Generic Drug Manufacturing: Key API for the production of cost-effective generic versions of antiretroviral drugs.

Basic Information

Product Name	Amprenavir
CAS No.	161814-49-9
Molecular Formula	C25H35N3O6S
Molecular Weight	505.63 g/mol
Synonyms	VX-478; AG1343; (3S)-Tetrahydro-3-furyl N-[(1S,2R)-3-[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamate; 141W94; Prozei; Amprenavirum; Amprenavirum [Latin]; UNII-YF3VKQ52K6
EINECS	Contact for details

Quality Control

Our Amprenavir CAS NO 161814-49-9 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.