Description

15(S)-Haea is a high-purity, stereospecific eicosanoid derivative, a key intermediate in the synthesis of specialized pro-resolving mediators (SPMs). This compound matters for researchers and manufacturers focused on developing advanced therapeutics for inflammation resolution and immune modulation. It is essential for pharmaceutical R&D, particularly in the fields of metabolic disease, cardiovascular research, and the development of novel anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of bioactive lipid mediators like resolvins and protectins.
• Biochemical Research: Used as a reference standard and tool compound in studies of eicosanoid signaling pathways and inflammation resolution mechanisms.
• Drug Discovery: Serves as a key building block in medicinal chemistry programs targeting chronic inflammatory diseases, such as arthritis, asthma, and atherosclerosis.
• Academic Research: Employed in university and institutional labs for investigating the role of lipid autacoids in cellular physiology and disease models.
• Diagnostic Development: Potential use in calibrating analytical methods (LC-MS/MS) for quantifying SPMs in biological samples.

Basic Information

Product Name	15(S)-Haea
CAS No.	161744-53-2
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	15(S)-HETE-EA; 15(S)-Hydroxyeicosatetraenoic Acid Ethanolamide; 15(S)-HETE Ethanolamide; 15S-HETE-EA; 15S-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid Ethanolamide; (15S)-HETE-EA; 15S-HETE Ethanolamide; 15(S)-HETE-Ethanolamide
EINECS	Contact for details

Quality Control

Our 15(S)-Haea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. A detailed Certificate of Analysis (COA) providing batch-specific data on identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and hygroscopic nature. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98% (15S-isomer)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.