Description

(4S,4'S)-2,2'-(Pentane-3,3'-Diyl)Bis(4-Benzyl-4,5-Dihydrooxazole) is a high-value, chiral bis(oxazoline) ligand, a critical class of compounds in modern asymmetric synthesis. Its precise stereochemistry and rigid structure make it an indispensable tool for creating highly enantioselective metal catalysts. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require superior stereocontrol in catalytic transformations such as cyclopropanations, Diels-Alder reactions, and various carbon-heteroatom bond formations.

Application

• As a chiral ligand for asymmetric catalysis in pharmaceutical intermediate synthesis.
• Key component in the development of enantioselective catalysts for cyclopropanation reactions.
• Utilized in asymmetric Diels-Alder reactions for the construction of complex chiral frameworks.
• Facilitates carbon-heteroatom bond-forming reactions (e.g., C-N, C-O) with high enantiomeric excess.
• Critical for academic and industrial R&D in novel catalytic methodologies.
• Used in the synthesis of agrochemicals requiring specific stereoisomers for optimal activity.
• Employed in the production of flavors, fragrances, and advanced materials where chirality dictates properties.

Basic Information

Product Name	(4S,4'S)-2,2'-(Pentane-3,3'-Diyl)Bis(4-Benzyl-4,5-Dihydrooxazole)
CAS No.	160191-64-0
Molecular Formula	C31H34N2O2
Molecular Weight	466.62 g/mol
Synonyms	(S,S)-3,3'-Pentylenebis(4-benzyl-2-oxazoline); (4S,4'S)-2,2'-(Pentane-3,3-diyl)bis(4-benzyl-4,5-dihydrooxazole); (S,S)-Pentylenebis(4-benzyl-2-oxazoline); (S,S)-PB-BOX; Chiral Bis(oxazoline) Ligand; (S,S)-4,4'-Bis(benzyl)-2,2'-(pentane-3,3-diyl)bis(4,5-dihydrooxazole); (S,S)-Benzyl-BOX-Pentyl Ligand
EINECS	Contact for details

Quality Control

Our (4S,4'S)-2,2'-(Pentane-3,3'-Diyl)Bis(4-Benzyl-4,5-Dihydrooxazole) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. We support cGMP and ISO compliant documentation for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.