Description

(S)-(-)-3-Bis(Methoxycarbonyl)Methyl-1-Cyclopentanone CAS NO 160115-23-1 is a high-purity chiral intermediate featuring a cyclopentanone core with two methoxycarbonylmethyl substituents. This compound matters for its role as a critical building block in the synthesis of complex, stereochemically defined molecules, enabling the production of advanced pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of enantiomerically pure intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a precursor in stereoselective reactions, including Michael additions, alkylations, and ring-forming transformations, to construct complex molecular architectures.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental profile.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for use in enantioselective catalysis.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic and Contract Research: A valuable reagent for methodological development and discovery chemistry in academic laboratories and contract research organizations (CROs).

Basic Information

Product Name	(S)-(-)-3-Bis(Methoxycarbonyl)Methyl-1-Cyclopentanone
CAS No.	160115-23-1
Molecular Formula	C11H16O5
Molecular Weight	228.24 g/mol
Synonyms	(S)-3-Bis(methoxycarbonyl)methylcyclopentanone; (3S)-3-[(Methoxycarbonyl)methyl]-3-[(methoxycarbonyl)methyl]cyclopentanone; (S)-3,3-Bis(methoxycarbonylmethyl)cyclopentanone; (S)-(-)-3,3-Bis(methoxycarbonylmethyl)cyclopentanone; (S)-3,3-Bis(methoxycarbonylmethyl)cyclopentan-1-one; (S)-3,3-Bis(carbomethoxymethyl)cyclopentanone; (S)-3,3-Di(methoxycarbonylmethyl)cyclopentanone; (S)-3,3-Di(carbomethoxymethyl)cyclopentanone
EINECS	Contact for details

Quality Control

Our (S)-(-)-3-Bis(Methoxycarbonyl)Methyl-1-Cyclopentanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.