Description

2-Deoxy-D-[5-13C]Erythro-Pentose is a stable isotope-labeled derivative of 2-deoxy-D-ribose, where the carbon-5 position is enriched with the 13C isotope. This compound is a critical tool for advanced metabolic and biochemical research, enabling precise tracking and quantification of nucleotide and nucleic acid synthesis pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, metabolic flux analysis, and the development of diagnostic agents.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled precursor in NMR and mass spectrometry studies to elucidate the pentose phosphate pathway and nucleotide biosynthesis.
• Pharmaceutical R&D: Serves as a key intermediate in the synthesis of isotopically labeled nucleoside analogs for pharmacokinetic and pharmacodynamic studies.
• Biochemical Research: Enables detailed investigation into DNA repair mechanisms and the metabolism of anticancer and antiviral nucleoside drugs.
• Diagnostic Agent Development: Employed in the creation of contrast agents or probes for molecular imaging techniques like PET (Positron Emission Tomography) when further radiolabeled.
• Stable Isotope Labeling: Essential for producing internally standardized compounds for accurate quantitative analysis in complex biological matrices.

Basic Information

Product Name	2-Deoxy-D-[5-13C]Erythro-Pentose
CAS No.	159838-86-5
Molecular Formula	C5H1013CO4
Molecular Weight	135.12 g/mol (for 13C1 labeled form)
Synonyms	2-Deoxy-D-ribose-5-13C; [5-13C]-2-Deoxy-D-erythro-pentose; 2-Deoxy-D-[5-13C]ribose; 2-Deoxy-D-erythro-pentofuranose-5-13C; 2-Deoxy-D-[5-13C]erythropentose; 2-Deoxy-D-[5-13C]erythro-pentofuranose; Isotopically labeled 2-deoxyribose; 2-Deoxy-D-ribose (5-13C)
EINECS	Contact for details

Quality Control

Every batch of 2-Deoxy-D-[5-13C]Erythro-Pentose is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing via NMR, HPLC, and mass spectrometry to confirm structure, enrichment level, and absence of impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the isotopic enrichment, chemical purity, and specific analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
13C Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.