Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Ethenyl-, (1R,2S)- (9Ci) is a high-purity, chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical, structurally constrained building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate its unique three-membered ring pharmacophore into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides where the cyclopropane ring enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide analogs to induce specific conformational constraints and improve metabolic stability.
• Material Science Precursor: Potential use in synthesizing specialized monomers for advanced polymeric materials.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Ethenyl-, (1R,2S)- (9Ci)
CAS No.	159700-58-0
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	(1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic acid; (1R,2S)-1-Amino-2-ethenylcyclopropanecarboxylic acid; (1R,2S)-AVCP; trans-1-Amino-2-vinylcyclopropanecarboxylic acid; (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic acid; Vinyl-ACPC; (1R,2S)-VACPC; 1-Amino-2-vinylcyclopropanecarboxylic acid (1R,2S)-isomer
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-Ethenyl-, (1R,2S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.