Description

(S)-2-Phenyloxetane is a chiral oxetane building block of significant interest in modern organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical sector where its rigid, three-dimensional structure can be used to modulate the biological activity and metabolic stability of drug candidates. It is primarily needed by research chemists and process development scientists in pharmaceutical R&D, agrochemical discovery, and advanced material science for applications in asymmetric synthesis and medicinal chemistry.

Application

• As a key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• Building block for novel ligands and catalysts used in enantioselective transformations.
• Intermediate in the research and development of agrochemicals and fine chemicals.
• Precursor for materials science applications, including the synthesis of functional polymers.
• Use in academic and industrial research for exploring new chemical space and structure-activity relationships (SAR).

Basic Information

Product Name	(S)-2-Phenyloxetane
CAS No.	159652-77-4
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	(S)-2-Phenyloxetane; (S)-2-Phenyl-oxetane; (S)-Phenyloxetane; (S)-2-Phenyl-1,3-propylene oxide; (S)-2-Phenyloxacyclobutane; Oxetane, 2-phenyl-, (2S)-; (2S)-2-Phenyloxetane
EINECS	Contact for details

Quality Control

Our (S)-2-Phenyloxetane is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiling via techniques such as GC, HPLC, and NMR. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.