Description

Enfuvirtide is a synthetic peptide of 36 amino acids that functions as a potent and specific HIV fusion inhibitor. This compound is critical for advanced antiviral research and therapeutic development, targeting the gp41 protein of HIV-1 to prevent viral entry into host cells. It is primarily utilized by pharmaceutical manufacturers, biotechnology research institutions, and academic laboratories engaged in the development of novel antiretroviral drugs and the study of viral entry mechanisms.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of antiretroviral medications.
• Biomedical Research as a critical tool for studying HIV-1 fusion and entry pathways.
• Drug Discovery & Development for screening and evaluating new combination therapies against resistant HIV strains.
• Reference Standard in analytical laboratories for quality control and method validation of related pharmaceutical products.
• Preclinical & Clinical Studies to investigate pharmacokinetics, efficacy, and novel delivery systems for peptide-based therapeutics.

Basic Information

Product Name	Enfuvirtide
CAS No.	159519-65-0
Molecular Formula	C204H301N51O64
Molecular Weight	4491.9 g/mol
Synonyms	T-20; DP-178; Pentafuside; Fuzeon (Brand Name); HIV-1 Fusion Inhibitor T-20; Enfuvirtide Acetate; N-Acetyl-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
EINECS	Contact for details

Quality Control

Our Enfuvirtide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent tests for related substances and residual solvents, ensuring it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) are provided and can be tailored to support regulatory filings for drug master files (DMF) or investigational new drug (IND) applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored in a dry environment. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 8.0%
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg
Microbial Enumeration	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.