Description

Saredutant is a potent and selective non-peptide antagonist of the neurokinin 2 (NK2) receptor. This compound is a critical research tool for investigating the role of the tachykinin system in physiological and pathophysiological processes. It is primarily utilized in advanced pharmaceutical research and development, particularly in studies related to gastrointestinal motility, asthma, and central nervous system disorders. Saredutant CAS NO 159125-41-4 represents a high-purity standard for reliable and reproducible experimental results.

Application

• Pharmacological Research: As a reference standard in studies exploring NK2 receptor function and signal transduction pathways.
• Drug Discovery & Development: Used in high-throughput screening and lead optimization for novel therapeutics targeting tachykinin receptors.
• Preclinical Studies: Investigation of potential treatments for conditions like irritable bowel syndrome (IBS), chronic cough, and anxiety/depression models.
• Biochemical Assays: Serves as a control compound in receptor binding and functional assays (e.g., calcium flux, cAMP).
• Academic Research: Fundamental neuroscience and physiology research in university and institutional laboratories.

Basic Information

Product Name	Saredutant
CAS No.	159125-41-4
Molecular Formula	C₂₀H₂₅ClN₂O₃
Molecular Weight	376.88 g/mol
Synonyms	SR 48968; Saredutant Hydrochloride; SR-48968; (S)-N-Methyl-N[4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl]benzamide; 1-Piperidinecarboxamide, N-[2-[4-(4-acetylamino-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl]-N-methyl-; SR48968
EINECS	Contact for details

Quality Control

Our Saredutant is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.