Description

2-Amino-3,4-Difluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and an amino group on the aromatic ring, enabling precise modulation of electronic properties and bioactivity in target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular interactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the difluoro motif enhances stability and bioavailability.
• Ligand and Catalyst Development: Employed in creating specialized ligands for transition metal catalysis and asymmetric synthesis.
• Material Science Research: Serves as a monomer or functionalizing agent for advanced polymers and liquid crystals with specific electronic properties.
• Fluorescent Probe and Dye Chemistry: Acts as a core structure for synthesizing fluorophores and imaging agents used in biochemical assays.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to diverse R&D projects.

Basic Information

Product Name	2-Amino-3,4-Difluorobenzoic Acid
CAS No.	158580-94-0
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	3,4-Difluoroanthranilic Acid; Benzoic acid, 2-amino-3,4-difluoro-; 2-Amino-3,4-difluorobenzoic acid; 3,4-Difluoro-2-aminobenzoic Acid; 158580-94-0; 2-Amino-3,4-difluoro-benzoic acid; 3,4-Difluoroanthranilsaeure (German)
EINECS	Contact for details

Quality Control

Our 2-Amino-3,4-Difluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.