Description

Morpholine, 2-(Methoxymethyl)-, (2S)- CAS NO 157791-20-3 is a high-purity, chiral morpholine derivative of significant interest in advanced organic synthesis. Its value lies in its role as a versatile chiral building block and ligand, enabling the production of enantiomerically pure compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create active ingredients with specific stereochemistry. Its defined stereocenter makes it a critical intermediate for asymmetric synthesis and catalyst development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor or component in chiral ligands for transition metal catalysis, facilitating enantioselective reactions like hydrogenation or cross-coupling.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides, fungicides, and insecticides where specific stereochemistry impacts biological activity.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for complex, high-value specialty chemicals requiring a defined (S)-configuration.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, exploring new asymmetric transformations and synthetic pathways.

Basic Information

Item	Detail
Product Name	Morpholine, 2-(Methoxymethyl)-, (2S)-
CAS No.	157791-20-3
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(S)-2-(Methoxymethyl)morpholine; (2S)-2-(Methoxymethyl)morpholine; L-2-(Methoxymethyl)morpholine; (S)-(-)-2-(Methoxymethyl)morpholine; (S)-Morpholin-2-ylmethanol methyl ether; 2-(Methoxymethyl)-, (2S)-morpholine; (2S)-2-(Methoxymethyl)-1,4-oxazinane
EINECS	Contact for details

Quality Control

Our (S)-2-(Methoxymethyl)morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for advanced synthetic applications. Certificates of Analysis (COA) with full chromatographic data, including enantiomeric excess (ee), are provided for every shipment. We support cGMP compliance for pharmaceutical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.