Description

tert-Butyl 3-Fluoro-4-Nitrobenzoate is a high-purity, synthetically valuable benzoate ester derivative. This compound serves as a crucial advanced pharmaceutical intermediate and versatile building block in organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, pesticides, and fungicides where the fluorine and nitro functional groups impart specific biological activity.
• Organic Building Block: Employed in cross-coupling reactions, esterifications, and nucleophilic aromatic substitutions to construct more complex molecular architectures.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.
• Chemical Reference Standard: Supplied to analytical laboratories for use as a high-purity calibration standard in chromatographic analysis.

Basic Information

Product Name	tert-Butyl 3-Fluoro-4-Nitrobenzoate
CAS No.	157665-52-6
Molecular Formula	C11H12FNO4
Molecular Weight	241.22 g/mol
Synonyms	3-Fluoro-4-nitrobenzoic acid tert-butyl ester; Benzoic acid, 3-fluoro-4-nitro-, 1,1-dimethylethyl ester; tert-Butyl 3-fluoro-4-nitrobenzoate; 1,1-Dimethylethyl 3-fluoro-4-nitrobenzoate; 3-Fluoro-4-nitro-benzoic acid tert-butyl ester; 4-Nitro-3-fluorobenzoic acid tert-butyl ester; t-Butyl 3-fluoro-4-nitrobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Fluoro-4-Nitrobenzoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.