Description

3,4-Difluoro-2-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and a methyl group on the aromatic ring, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluoromethylbenzoic acid moiety contributes to biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with enhanced chemical resistance and thermal stability.
• Organic Electronic Materials: Utilized in the development of organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for exploring new fluorination chemistry and structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Item	Detail
Product Name	3,4-Difluoro-2-Methylbenzoic Acid
CAS No.	157652-31-8
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2-Methyl-3,4-difluorobenzoic Acid; 3,4-Difluoro-o-toluic Acid; 3,4-Difluoro-2-methylbenzenecarboxylic acid; 157652-31-8; Benzoic acid, 3,4-difluoro-2-methyl-; 2-Methyl-3,4-difluorobenzoic acid; 3,4-Difluoro-2-methyl-benzoic acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Methylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency for research and production use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.