Description

2,3,4-Trifluoro-6-(Trifluoromethyl)Benzoic Acid is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group and three fluorine atoms on the benzoic acid core, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Modification: Incorporated as a monomer or modifier to create specialty polymers with improved chemical resistance, thermal stability, and low surface energy.
• Organic Electronics: Utilized in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors due to its electron-withdrawing properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library synthesis.

Basic Information

Product Name	2,3,4-Trifluoro-6-(Trifluoromethyl)Benzoic Acid
CAS No.	157337-84-3
Molecular Formula	C8H2F6O2
Molecular Weight	244.09 g/mol
Synonyms	6-(Trifluoromethyl)-2,3,4-trifluorobenzoic Acid; 2,3,4-Trifluoro-α,α,α-trifluoro-o-toluic Acid; Benzoic acid, 2,3,4-trifluoro-6-(trifluoromethyl)-; 2,3,4-Trifluoro-6-trifluoromethylbenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,3,4-Trifluoro-6-(Trifluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we support custom purity grades for specific R&D or cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.