Description

Isotrazodone CAS NO 157072-18-9 is a high-purity chemical compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical profiling of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) active drugs. Our supply ensures consistent quality and reliable availability for your most demanding R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for novel psychotropic and neuroactive drug candidates.
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control testing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in preclinical studies to investigate pharmacological mechanisms and structure-activity relationships (SAR).
• Metabolite Studies: Utilized as a standard in the identification and quantification of drug metabolites during pharmacokinetic and toxicological research.
• Process Chemistry: Serves as a starting material or intermediate in optimizing commercial-scale synthesis routes for related compounds.

Basic Information

Product Name	Isotrazodone
CAS No.	157072-18-9
Molecular Formula	C19H22ClN5O
Molecular Weight	371.86 g/mol
Synonyms	Isotrazodone; 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one; 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-; Trazodone Impurity; Isotrazodone Hydrochloride (salt form); Trazodone Related Compound
EINECS	Contact for details

Quality Control

Every batch of Isotrazodone is manufactured and tested under strict quality management systems. We provide material that meets high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (e.g., HPLC, NMR) is supplied with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.