Description

(3S,3Ar,6As)-Hexahydrofuro[2,3-B]Furan-3-Ol CAS NO 156928-10-8 is a high-purity, chiral furan-based alcohol building block of significant interest in advanced organic synthesis. Its unique fused bicyclic structure and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce complex, oxygen-containing heterocyclic motifs into target molecules.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemical purity.
• Academic and Industrial Research: Used in chemical biology and material science research to explore new synthetic methodologies and compound libraries.

Basic Information

Product Name	(3S,3Ar,6As)-Hexahydrofuro[2,3-B]Furan-3-Ol
CAS No.	156928-10-8
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol; (3S,3aR,6aS)-Octahydro-2H-furo[2,3-b]furan-3-ol; Hexahydrofuro[2,3-b]furan-3-ol, (3S,3aR,6aS)-; L-Norvaline, 5-oxo-, cyclic (3S,3aR,6aS)-octahydro-2H-furo[2,3-b]furan-3-yl ester; Chiral Furan Alcohol Building Block; Bicyclic Furanol
EINECS	Contact for details

Quality Control

Our (3S,3Ar,6As)-Hexahydrofuro[2,3-B]Furan-3-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical assay, and impurity profile. We support cGMP compliance for advanced applications and can provide material tailored to specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.