Description

Epi Norgalanthamine CAS NO 156040-03-8 is a high-purity galanthamine derivative, a key intermediate in the synthesis of bioactive alkaloids. This compound is valued for its precise stereochemistry and consistent quality, which are critical for advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel acetylcholinesterase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of galanthamine analogs and related alkaloid-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development and study of new compounds targeting acetylcholinesterase for potential applications in cognitive disorders.
• Process Chemistry: Serves as a reference standard and starting material for route scouting and optimization in complex organic synthesis.
• Fine Chemical Synthesis: Employed in the preparation of specialized chiral molecules for advanced material science and agrochemical research.
• Analytical Standard: Used as a high-purity standard in HPLC, LC-MS, and NMR for method development and quality control in analytical laboratories.

Basic Information

Product Name	Epi Norgalanthamine
CAS No.	156040-03-8
Molecular Formula	C16H19NO3
Molecular Weight	273.33 g/mol
Synonyms	Epi-Norgalanthamine; (-)-Epi-Norgalanthamine; (3S,4aR,6S,8aS)-3,4,4a,6,7,8,8a,9-Octahydro-6-hydroxy-3-methyl-1H-[2]benzopyrano[3,4-g]indol-9-one; 9-Oxo-10-azagalanthamine; N-Desmethylgalanthamine epimer; Galanthamine derivative intermediate
EINECS	Contact for details

Quality Control

Our Epi Norgalanthamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.