Description

(R)-1-[(1S)-2-(Diphenylphosphino)Ferrocenyl]Ethyldi-tert-Butylphosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, crucial for producing single-isomer pharmaceuticals and fine chemicals with superior efficiency and selectivity. This ligand is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in hydrogenation, cross-coupling, and other transition metal-catalyzed reactions.

Application

• As a privileged chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure amino acids, amines, and other pharmaceutical intermediates.
• Catalyst component for enantioselective cross-coupling reactions (e.g., Suzuki-Miyaura, Negishi) to construct chiral biaryl and other complex molecular architectures.
• Key reagent in the development of homogeneous catalysts for the production of high-value specialty and fine chemicals.
• Use in academic and industrial R&D for methodological studies in asymmetric synthesis and catalyst design.
• Potential applications in material science for creating chiral surfaces or polymers with specific optical properties.

Basic Information

Product Name	(R)-1-[(1S)-2-(Diphenylphosphino)Ferrocenyl]Ethyldi-tert-Butylphosphine
CAS No.	155830-69-6
Molecular Formula	C34H40FeP2
Molecular Weight	566.46 g/mol
Synonyms	(R)-(S)-Josiphos; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyldi(tert-butyl)phosphine; Josiphos SL-J009-1; (R)-(S)-PPF-t-Bu2; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl-di-tert-butylphosphine; Di-tert-butyl((R)-1-((S)-2-(diphenylphosphino)ferrocenyl)ethyl)phosphine; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl-di-tert-butylphosphine
EINECS	Contact for details

Quality Control

Our production of (R)-1-[(1S)-2-(Diphenylphosphino)Ferrocenyl]Ethyldi-tert-Butylphosphine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, which is critical for catalytic performance. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a dry environment before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.