Description

3-Fluoro-2-Methylcinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methyl substituents, makes it a valuable scaffold for modulating the physicochemical properties of target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors, anti-inflammatory agents, and other bioactive molecules.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators where the fluorine atom enhances metabolic stability and bioavailability.
• Material Science: Acts as a monomer or functionalizing agent for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile building block for Suzuki-Miyaura and other cross-coupling reactions to construct complex, fluorinated aromatic systems.
• Life Science Research: Employed as a biochemical probe or a labeled compound in metabolic and pharmacokinetic studies.
• Fine Chemical Production: Intermediate for synthesizing flavors, fragrances, and advanced organic dyes.

Basic Information

Product Name	3-Fluoro-2-Methylcinnamic Acid
CAS No.	155814-23-6
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	(E)-3-(3-Fluoro-2-methylphenyl)acrylic acid; 3-Fluoro-2-methylcinnamate; 2-Methyl-3-fluorocinnamic acid; (E)-3-Fluoro-2-methylcinnamic acid; trans-3-Fluoro-2-methylcinnamic acid; 3-Fluoro-o-methylcinnamic acid; α-Methyl-3-fluorocinnamic acid; (2E)-3-(3-Fluoro-2-methylphenyl)prop-2-enoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methylcinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing exact specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	<20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.