Description

(2R,5R)-2,5-Diphenylpyrrolidine is a high-purity chiral pyrrolidine derivative, a valuable building block in asymmetric synthesis and pharmaceutical research. Its defined stereochemistry makes it a critical ligand and intermediate for creating enantiomerically pure compounds, directly impacting the efficacy and safety of final products. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-quality chiral auxiliaries.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold or ligand in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalysis: Employed as a chiral ligand or organocatalyst in enantioselective transformations such as hydrogenations, alkylations, and cycloadditions.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a precursor for chiral polymers, liquid crystals, and other functional materials with specific optical properties.
• Academic & R&D: A fundamental tool in university and corporate research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(2R,5R)-2,5-Diphenylpyrrolidine
CAS No.	155155-73-0
Molecular Formula	C16H17N
Molecular Weight	223.31 g/mol
Synonyms	(2R,5R)-2,5-Diphenylpyrrolidine; (R,R)-2,5-Diphenylpyrrolidine; (2R,5R)-2,5-Diphenyl-1-azacyclopentane; (R,R)-2,5-Diphenyl-1-azacyclopentane; (2R,5R)-2,5-Diphenyltetrahydropyrrole; NSC 339586; (R,R)-DPP; (2R,5R)-DPP
EINECS	Contact for details

Quality Control

Our (2R,5R)-2,5-Diphenylpyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.