Description

Efavirenz CAS NO 154635-17-3 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) used in antiretroviral therapy. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of effective and reliable HIV-1 treatment regimens. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antiretroviral medications.

Application

• Primary active ingredient in the formulation of antiretroviral combination therapies for HIV-1 infection.
• Key component in the manufacture of fixed-dose combination (FDC) tablets for improved patient compliance.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Starting material or intermediate for the synthesis of novel antiviral compounds in research settings.
• Used in clinical research studies to evaluate new treatment protocols and drug delivery systems.

Basic Information

Product Name	Efavirenz
CAS No.	154635-17-3
Molecular Formula	C14H9ClF3NO2
Molecular Weight	315.67 g/mol
Synonyms	EFV; Sustiva®; DMP 266; (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one; (+)-Efavirenz; L-743,726
EINECS	Contact for details

Quality Control

Our Efavirenz is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 20 ppm
Loss on Drying	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.