Description

D-[3-13C]Glycerol is a stable isotope-labeled analog of glycerol, specifically enriched with carbon-13 at the third carbon position. This compound is an essential biochemical tracer for metabolic flux analysis and nuclear magnetic resonance (NMR) spectroscopy studies. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic manufacturers involved in advanced metabolic research, drug development, and biomarker discovery.

Application

• Metabolic Flux Analysis (MFA): Used as a labeled precursor to trace and quantify carbon flow through central metabolic pathways like glycolysis and gluconeogenesis.
• In Vivo Metabolic Studies: Enables non-invasive tracking of glycerol metabolism, lipid synthesis, and energy production in living systems using techniques such as 13C-MRS.
• Pharmaceutical R&D: Serves as a critical tool in drug discovery for studying the mechanism of action of metabolic inhibitors and evaluating drug efficacy on lipid metabolism.
• Diagnostic Probe Development: Employed in the synthesis of labeled probes for diagnostic assays and imaging agents to study metabolic disorders.
• Biochemical Research: Acts as a standard or internal standard in mass spectrometry (MS) and NMR for the accurate quantification of glycerol and its derivatives in complex biological matrices.
• Nutritional Science: Used in clinical studies to investigate human lipid metabolism, energy expenditure, and the metabolic effects of dietary interventions.

Basic Information

Product Name	D-[3-13C]Glycerol
CAS No.	154278-20-3
Molecular Formula	C313CH8O3
Molecular Weight	93.09 g/mol (for 13C1 isotopologue)
Synonyms	(2R)-1,2,3-Trihydroxypropane-3-13C; D-Glycerol-3-13C; (R)-Glycerol-3-13C; Glycerin-3-13C; 1,2,3-Propanetriol-3-13C (D-form); [3-13C]-D-Glycerol; D-Glycerol (3-13C); 13C-Labeled D-Glycerol
EINECS	Contact for details

Quality Control

Our D-[3-13C]Glycerol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and MS, to confirm isotopic enrichment (13C), chemical purity, enantiomeric excess, and absence of biological contaminants. Certificates of Analysis (COA) detailing isotopic purity (typically >99 atom % 13C), chemical purity (by HPLC), specific rotation, and other critical parameters are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (13C)	>99 atom %
Chemical Purity (HPLC)	>98.0%
Specific Rotation	+13.5° to +15.5° (c=10 in H2O)
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.