Description

Acetic Acid, [(2,6-Difluorobenzoyl)Amino]Hydroxy- (9Ci) is a specialized fluorinated organic building block and intermediate of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, which incorporates both a difluorobenzoyl group and an N-hydroxyacetamide moiety, enabling precise modifications in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where the difluorophenyl and hydroxamic acid groups are critical for bioactivity.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the fluorine atoms for enhanced metabolic stability and membrane permeability.
• Chemical Biology Probe Synthesis: Serves as a building block for creating activity-based probes and inhibitors for metalloproteases and other hydrolytic enzymes.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with specific surface properties or degradation profiles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	Acetic Acid, [(2,6-Difluorobenzoyl)Amino]Hydroxy- (9Ci)
CAS No.	153876-17-6
Molecular Formula	C9H7F2NO4
Molecular Weight	231.16 g/mol
Synonyms	N-Hydroxy-2,6-difluorobenzamide acetate; Acetic acid, compd. with N-hydroxy-2,6-difluorobenzamide (1:1); 2,6-Difluoro-N-hydroxybenzamide acetate; N-Hydroxy-2,6-difluorobenzamide acetic acid salt; [(2,6-Difluorobenzoyl)amino]hydroxy-acetic acid; AcOH salt of N-Hydroxy-2,6-difluorobenzamide
EINECS	Contact for details

Quality Control

Our Acetic Acid, [(2,6-Difluorobenzoyl)Amino]Hydroxy- (9Ci) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.