Description

1,2-Aziridinedicarboxylic acid, Dimethyl ester, (S)-(9Ci) is a high-purity chiral aziridine derivative, a crucial building block in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, enabling the development of advanced pharmaceuticals and agrochemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and oncological pathways.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysts employed in enantioselective reactions.
• Peptidomimetic & Protease Inhibitor Development: Incorporated into the backbone of peptide analogs and enzyme inhibitors due to its constrained three-membered ring structure.
• Agrochemical Research: Serves as an intermediate in creating novel, stereochemically pure herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science Monomers: Potential use in synthesizing specialized polymers with unique thermal or mechanical properties derived from the strained aziridine ring.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up studies for new chemical entities.

Basic Information

Product Name	1,2-Aziridinedicarboxylic acid, Dimethyl ester, (S)-(9Ci)
CAS No.	153381-07-8
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	(S)-Dimethyl Aziridine-1,2-dicarboxylate; (2S)-1,2-Aziridinedicarboxylic Acid Dimethyl Ester; (S)-1,2-Aziridinedicarboxylic Acid Dimethyl Ester; Dimethyl (S)-aziridine-1,2-dicarboxylate; (S)-DAAD; (S)-Dimethyl 1,2-aziridinedicarboxylate; Aziridine-1,2-dicarboxylic acid, dimethyl ester, (S)-; L-Aziridine-1,2-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and enantiomeric excess. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.