Description

Lanicemine Dihydrochloride CAS NO 153322-06-6 is a high-purity, non-competitive NMDA receptor antagonist with channel-blocking properties, primarily used in advanced pharmaceutical research and development. This compound is critical for investigating novel therapeutic pathways for central nervous system disorders, offering researchers a potent and selective tool for modulating glutamatergic signaling. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on neuropharmacology, depression, and chronic pain research.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in API manufacturing.
• Neuroscience Research: A key investigational tool for studying the role of NMDA receptors in synaptic plasticity, learning, and memory.
• Preclinical Drug Development: Used in in vitro and in vivo studies to explore potential treatments for treatment-resistant depression and mood disorders.
• Mechanistic Studies: Facilitates research into the pathophysiology of neuropathic pain and the development of novel analgesic agents.
• Biochemical Assays: Employed in high-throughput screening (HTS) and receptor binding assays to identify and characterize new chemical entities.

Basic Information

Product Name	Lanicemine Dihydrochloride
CAS No.	153322-06-6
Molecular Formula	C₁₇H₂₅Cl₂N₃O₂
Molecular Weight	374.30 g/mol
Synonyms	AZD6765 Dihydrochloride; (1S,2S)-3-(4-Chlorophenyl)-1,2-cyclopentanedicarboximide Dihydrochloride; (1S,2S)-1,2-Cyclopentanedicarboximide, 3-(4-chlorophenyl)-, dihydrochloride; Lanicemine HCl; AR-R 15896AR; AR-R15896AR; NMDA Receptor Antagonist AZD6765.
EINECS	Contact for details

Quality Control

Our Lanicemine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent control of residual solvents and impurities to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.